Amazon Truck Collision Causes Lane Closures on I-5 near San Ysidro Border Crossing

A serious traffic collision occurred on southbound Interstate 5 near the San Ysidro border crossing in California, according to a Sig Alert from the California Highway Patrol. The incident took place around 4 a.m. on Thursday, September 17, 2026.

An Amazon delivery truck crashed into a guardrail, jackknifing across at least two lanes of traffic. The driver's condition is unknown at this time.

The scene was complex due to fuel and other vehicle fluids spilled from the crash, affecting four lanes of traffic. The California Highway Patrol requested absorbent material to address the spill, with Caltrans also responding to the scene.